We would like to inform you of the changes according to the "Partial Amendment to the Designation of Human Acute Hazardous Substances, Human Chronic Hazardous Substances, and Ecological Hazardous Substances (Notification No. 2026-5)" by the National Institute of Chemical Safety(NICS).
Overview
On March 27, 2026, 74 types of human and ecological hazardous substances¹⁾ were newly designated based on the Act on the Registration and Evaluation, etc. of Chemical Substances.
With the enforcement of the regulation on July 1, 2026, obligations to verify and label chemical substances will be imposed across all processes of parts manufacturing.
1) Substances designated as human acute hazardous, human chronic hazardous, and ecological hazardous substances.
Key Content
1. Registration of 74 New Hazardous Substances
73 human acute hazardous substances and 1 multi-classified substance were newly designated. (Given Numbers: 2026-1-1281 to 2026-1-1354)
The 1 multi-classified²⁾ substance is Sodium Hypochlorite (CAS 7681-52-9). For this substance only, the regulation will take effect on January 1, 2028.
2) When a single substance simultaneously falls under two or more hazard classifications among human acute, human chronic, and ecological hazards.
2. Concentration Limits for Hazardous Chemical Determination
Most new substances are subject to a 10% limit, but some substances are regulated at lower concentrations.
5% Limit: N,N'-Diisopropylethylenediamine, 1-Ethylpiperazine, etc.
2.5% Limit: Sodium Hypochlorite (When applying the ecological hazard standard)
3. Revision of Existing Substance Names
The given names of 3 substances, including arsenic and its compounds, have been changed.
97-1-119: Arsenic and its compounds
97-1-379: Fluoroacetic acid and its salts
97-1-417: p-Dimethylaminobenzenediazo sulfonic acid and its salts
4. Legal Obligation Deadlines
Businesses that have been handling the newly designated substances prior to the enforcement date of the notification must fulfill their obligations within the following deadlines in accordance with the Chemicals Control Act (CCA).
Phase
| Deadline
| Key Obligations
|
|---|
Phase 1 | Jan 1, 2027 | Chemical substance verification, labeling of hazardous chemicals, import declaration of human/ecological hazardous substances, seller notification |
Phase 2 | Jul 1, 2027 | Compliance with hazardous chemical handling standards |
Phase 3 | Jul 1, 2028 | Preparation and submission of chemical accident prevention management plans, business permits and declarations for hazardous chemicals |
Phase 4 | Jul 1, 2030 | Compliance with installation and management standards for hazardous chemical handling facilities |
Conclusion
In line with the global trend of strengthening environmental regulations, the scope of domestic hazardous chemical regulations is also continuously expanding.
As the mandatory labeling of hazardous substances goes into full effect in 2027, we strongly recommend minimizing future supply chain risks through preliminary checks of your component data.
MDSKorea will continue to do our best to provide useful insights for professionals in the field.
Thank you.
We would like to inform you of the changes according to the "Partial Amendment to the Designation of Human Acute Hazardous Substances, Human Chronic Hazardous Substances, and Ecological Hazardous Substances (Notification No. 2026-5)" by the National Institute of Chemical Safety(NICS).
Overview
On March 27, 2026, 74 types of human and ecological hazardous substances¹⁾ were newly designated based on the Act on the Registration and Evaluation, etc. of Chemical Substances.
With the enforcement of the regulation on July 1, 2026, obligations to verify and label chemical substances will be imposed across all processes of parts manufacturing.
1) Substances designated as human acute hazardous, human chronic hazardous, and ecological hazardous substances.
Key Content
1. Registration of 74 New Hazardous Substances
73 human acute hazardous substances and 1 multi-classified substance were newly designated. (Given Numbers: 2026-1-1281 to 2026-1-1354)
The 1 multi-classified²⁾ substance is Sodium Hypochlorite (CAS 7681-52-9). For this substance only, the regulation will take effect on January 1, 2028.
2) When a single substance simultaneously falls under two or more hazard classifications among human acute, human chronic, and ecological hazards.
2. Concentration Limits for Hazardous Chemical Determination
Most new substances are subject to a 10% limit, but some substances are regulated at lower concentrations.
5% Limit: N,N'-Diisopropylethylenediamine, 1-Ethylpiperazine, etc.
2.5% Limit: Sodium Hypochlorite (When applying the ecological hazard standard)
3. Revision of Existing Substance Names
The given names of 3 substances, including arsenic and its compounds, have been changed.
97-1-119: Arsenic and its compounds
97-1-379: Fluoroacetic acid and its salts
97-1-417: p-Dimethylaminobenzenediazo sulfonic acid and its salts
4. Legal Obligation Deadlines
Businesses that have been handling the newly designated substances prior to the enforcement date of the notification must fulfill their obligations within the following deadlines in accordance with the Chemicals Control Act (CCA).
Phase 1
Jan 1, 2027
Chemical substance verification, labeling of hazardous chemicals, import declaration of human/ecological hazardous substances, seller notification
Phase 2
Jul 1, 2027
Compliance with hazardous chemical handling standards
Phase 3
Jul 1, 2028
Preparation and submission of chemical accident prevention management plans, business permits and declarations for hazardous chemicals
Phase 4
Jul 1, 2030
Compliance with installation and management standards for hazardous chemical handling facilities
For businesses handling Sodium Hypochlorite, a grace period of 1 year and 6 months is added to each of the respective deadlines above.
Conclusion
In line with the global trend of strengthening environmental regulations, the scope of domestic hazardous chemical regulations is also continuously expanding.
As the mandatory labeling of hazardous substances goes into full effect in 2027, we strongly recommend minimizing future supply chain risks through preliminary checks of your component data.
MDSKorea will continue to do our best to provide useful insights for professionals in the field.
Thank you.